Patients included in this study will be allocated to receive either standard practice (the oldest compatible available blood, 'front of the fridge') or freshest compatible available ('back of the fridge').  And will continue to receive the randomised treatment arm for any additional blood transfusion.

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Cooper J, McQuilten Z, Nichol A, Ady B, Aubron C, et al.  Age of Red Cells for Transfusion and Outcomes in Critically Ill Adults.  N Engl J Med 2017; 377: 1858-1867

Conclusion: The age of transfused red cells did not affect 90-day mortality among critically ill adults.